Glutathione S-Transferase M1 (GSTM1) Polymorphisms and Lung Cancer: A Literature-based Systematic HuGE Review and Meta-Analysis
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چکیده
منابع مشابه
Human Genome Epidemiology (HuGE) Review Glutathione S-Transferase M1 (GSTM1) Polymorphisms and Lung Cancer: A Literature-based Systematic HuGE Review and Meta-Analysis
1 Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada. 2 School of Environmental Health, University of British Columbia, Vancouver, British Columbia, Canada. 3 United Kingdom HuGENet Coordinating Centre, Strangeways Research Laboratory, University of Cambridge, Cambridge, United Kingdom. 4 MRC Biostatistics Unit, Institute of Public H...
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Smoking is a known risk factor for bladder cancer. The product of the GSTM1 gene, glutathione S-transferase M1 (GSTM1), is involved in the detoxification of polycyclic aromatic hydrocarbons found in tobacco smoke; a homozygous deletion of this gene in approximately 50% of Caucasians and Asians results in a lack of GSTM1 enzyme activity. Most studies examining the relation between bladder cancer...
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BACKGROUND Some studies have recently focused on the association between glutathione S-transferase M1 (GSTM1) and glutathione S-transferase T1 (GSTT1) null polymorphisms and hypertension; however, results have been inconsistent. OBJECTIVE In order to drive a more precise estimation, the present systematic review and meta-analysis is performed to investigate the relationship between the GSTM1 ...
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ژورنال
عنوان ژورنال: American Journal of Epidemiology
سال: 2008
ISSN: 1476-6256,0002-9262
DOI: 10.1093/aje/kwm383